TILE

Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome

Sponsor:

Sunnybrook Health Sciences Centre

Toronto, Canada   

Current Participant(s):

Canada, France

Status:

• Seeking sites and collaborators

Lead Network:

CanVECTOR

PLATO-VTE

Platelet mRNA profiling to detect occult cancer in unprovoked venous thromboembolism

Sponsor:

Academic Medical Center

Amsterdam, the Netherlands

Current Participant(s):

Belgium, Canada, Germany, Italy, Spain, The Netherlands, USA

Status:

• Seeking sites and collaborators

Lead Network:

DTN

RIVASVT-100

Treatment of portal, mesenteric, and splenic vein thrombosis with rivaroxaban. A pilot, prospective cohort study

Sponsor:

Università degli Studi dell'Insubria

Varese, Italy

Current Participant(s):

Canada, France, Germany, Italy

Status:

• Recruited started 2015
• Seeking sites and collaborators

Lead Network:

TRIP

VERDICT

Venous thromboembolism in renally impaired patients and direct oral anticoagulants

Sponsor:

Centre Hospitalier Universitaire de Saint Etienne

Saint Etienne, France

Current Participant(s):

Canada, France, Serbia, Spain, Switzerland

Status:

• Seeking sites and collaborators

Lead Network:

INNOVTE

RENOVE

REduced dose versus full-dose of direct oral anticoagulant after uNprOvoked Venous thromboEmbolism. The RENOVE open-label, randomized, controlled trial

Sponsor:

Brest University Hospital

Brest, France

Current Participant(s):

France

Status:

• Seeking sites and collaborators

Lead Network:

INNOVTE

SAVER/SPIRIT

StAtins for Venous Event Reduction in Patients With Venous Thromboembolism: A Pilot Study Assessing Feasibility of an RCT to Evaluate if Generic Rosuvastatin Reduces the Risk of Recurrent VTE in Patients With Symptomatic Major VTE

Current Participant(s):

Canada, Norway

Status:

• Pilot trial recruiting in Canada and Norway
• Seeking sites and collaborators for the full trial

Lead Network:

CanVECTOR

THEIA

Advanced diagnostic management of suspected recurrent ipsilateral deep vein thrombosis of the leg with magnetic resonance direct thrombus imaging

Current Participant(s):

Canada, Norway, Sweden, The Netherlands

Status:

• Completed recruitment
• Late Breaking Trials - ISTH 2019 Congress

Lead Network:

DTN

HIGHLOW

Low-molecular-weight heparin to prevent recurrent VTE in pregnancy: a randomized controlled trial of two doses

Current Participant(s):

Belgium, Canada, France, Ireland, Norway, The Netherlands, USA

Status:

• Recruiting
• Seeking sites and collaborators

Lead Network:

DTN

ALIFE2

Anticoagulants for living fetuses in women with recurrent miscarriage and inherited thrombophilia

Current Participant(s):

Belgium, Canada, The Netherlands, USA

Status:

• Recruiting
• Seeking sites and collaborators

Lead Network:

DTN

PEITHO-III

A reduced dose of thrombolytic treatment for patients with intermediate high-risk acute pulmonary embolism

Sponsor:

Hopital Européen Georges Pompidou, Assistance Publique Hopitaux de Paris, Université Paris Descartes

Current Participant(s):

Belgium, Canada, France, Germany, Italy, Poland, Romania, Spain, The Netherlands

Status:

• Seeking sites and collaborators

Lead Network:

INNOVTE

Pilot PARTUM Trial

Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity

Sponsor:

Foot Hills Medical Centre

Calgary, Canada

Current Participant(s):

Canada, The Netherlands, USA

Status:

Planning to begin recruitment in January 2020

Lead Network:

CanVECTOR

ADJUST-DVT

Age-adjusted d-dimer cutoff levels to rule out deep vein thrombosis

Sponsor:

University Hospital

Geneva, Switzerland

Current Participant(s):

Canada, Switzerland

Status:

• Recruiting 
• Seeking sites & collaborators 

Lead Network:

INNOVTE

The REDUCE Study

Management of recurrent venous thromboembolism during anticoagulant treatment in cancer patients - a prospective cohort study

Sponsor:

Amsterdam University Medical Center

Amsterdam, the Netherlands

Current Participant(s):

Italy, The Netherlands

Lead Network:

DTN

The Rhea Study

Optimizing diagnosis of splanchnic vein thrombosis with MR direct thrombus imaging

Sponsor:

• The Netherlands: Dutch Thrombosis Network  (Leiden University Medical Center, Leiden; Erasmus Medisch Centrum, Rotterdam)
• Italy: Thrombosis Research Italian Partnership (Varese University Hospital, Varese)

Current Participant(s):

Italy, The Netherlands

Lead Network:

DTN

COBRRA

Comparison of Bleeding Risk Between Rivaroxaban and Apixaban for the Treatment of Acute Venous Thromboembolism

Sponsor:

CIHR (Canadian Institutes of Health Research)

Current Participant(s):

Australia & New Zealand, Canada

Lead Network:

CanVECTOR