International Network of VENous Thromboembolism Clinical Research Networks

Flag of The Netherlands


Endorsed Studies:

The Dutch Thrombosis Network (DTN) is an independent, not-for-profit network of academic and non-academic clinical and basic researchers in thrombosis. DTN exists to promote national collaboration between academic and nonacademic researchers that conduct venous thromboembolism (VTE) related clinical research, and to enhance the profile, science, and impact of investigator-led VTE clinical research. DTN seeks to enable research by its members and to promote a culture of curiosity, scientific rigor and social responsibility in the conduct of VTE clinical research.

Council Members

Menno Huisman

Menno Huisman, MD, PhD

Prof. Dr. Menno Huisman’s research is focused on the clinical aspects of venous and arterial thromboembolic disorders, with special interest on the diagnosis and treatment of pulmonary embolism and deep-vein thrombosis. Pulmonary embolism (PE) and deep-vein thrombosis (DVT) are prevalent diseases, occurring in around 1-2/1000 inhabitants per year. Although the two diseases have distinct clinical presentations, they are often coined together as venous thromboembolism (VTE). A better diagnosis of both first and recurrent episodes as well as a more patient tailored treatment will lead a better outcome and will benefit patients with these disorders.

The research aims to optimalize diagnosis of first and recurrent episodes of acute and chronic pulmonary embolism and deep-vein thrombosis and to define optimal treatment, tailored to patient’s risks. To accomplish this, a clinical thrombosis research network – which is now part of the newly formed Dutch Thrombosis Network (DTN) - has been formed with hospitals in the Netherlands. The clinical research is investigated in large cohorts of consecutive patients presenting to the Emergency department and clinical ward of the cooperating hospitals, using predefined databases, accessible by internet applications, as well as dedicated biobanking for answering translational research questions.

Saskia Middeldorp

Saskia Middeldorp, MD, PhD

Saskia Middeldorp is qualified as a medical doctor at the University of Amsterdam in 1992. She received her training in internal medicine at the Academic Medical Center in Amsterdam and obtained her board licence in 1999 (subspecialty Vascular Medicine, 2002). Since December 2010, she is professor and co-chair of the Department of Vascular Medicine of the Academic Medical Center.

She leads the residency program of vascular medicine. Furthermore, she coordinates the module Clinical Scientific Methods of the Bachelor program of the medical faculty of the University of Amsterdam.

Prof. dr. Middeldorp looks after all patients with vascular medical diseases, with a focus on thrombosis and bleeding. She is considered an expert in women’s issues of thrombosis, such as pregnancy-related thrombosis, thrombophilia and pregnancy complications, and questions regarding the use of hormones in women with an increased tendency of thrombosis.

Her present research focuses on several aspects of hereditary and acquired thrombophilia, women’s issues in thrombosis and haemostasis, and the clinical evaluation of new anticoagulants.


* indicates required

Contact Permissions

Please select the ways you would like to hear from INVENT Network:

Contact Permissions

By clicking below to subscribe, you agree to the terms of our privacy policy.