Global Thrombosis Research Seminars

The INVENT-VTE Network Global Thrombosis Research Seminar Series showcases inspiring and high-impact thrombosis research initiatives, collaborations, and advancements from INVENT network-member countries.

The series is designed to showcase network-related research and initiatives that highlight:

• Endorsed Research and its contributions to the field
• Collaborations that drive practice-changing VTT research
• Key developments within national networks that enhance clinical VTE research.
• The critical role of international collaboration and INVENT’s leadership in fostering global research efforts.
• Innovative research initiatives that inspire and strengthen thrombosis research networks worldwide.

2025 Seminar Series

The 2025 series will feature three seminars throughout the year, each showcasing an INVENT-endorsed study with a special focus on its methodology. Every session will include presentations by international experts from across the INVENT-VTE Network, followed by a 15-minute Q&A to foster discussion and engagement.

Part 1: RENOVE TRIAL - Methodology, Study Design, & its Effect on Interpreting Results (Non-inferiority Vs Superiority Trials)

📅 Date: Wednesday, April 9, 2025
⏰ Time: 14:00 UTC 
💻 Location: Virtual Seminar via zoom

Featured Speakers:

• Francis Couturaud, MD, PhD – Brest University, France
• Émilie Presles – CHU Saint Etienne, France

The RENOVE Trial, an INVENT-endorsed study recently published in The Lancet, provides crucial insights into thrombosis treatment strategies. 📖 Read the full article here.

Recording:

Part 2: PARTUM TRIAL - Pragmatic Trials and Challenges with Complex Study Populations: Lessons learned from the pilot PARTUM trial and qualitative research.

📅 Date: Wednesday, June 4, 2025
⏰ Time: 14:00 UTC
💻 Location: Virtual Seminar via zoom

Featured Speakers

• Leslie Skeith, MD, MSc - University of Calgary, Alberta, Canada.

Live Q&A

• Attendees will also have the opportunity to participate in a 15-minute Q&A session, with the option to submit questions in advance.

About the Research

• The Pilot PARTUM Trial: Low-dose aspirin versus placebo in postpartum venous thromboembolism: a multi-national, pilot, randomised, placebo-controlled trial - The Lancet Haematology. Read the full article here. 📖
• Patient and healthcare providers’ perspectives on participation in a postpartum pilot trial of venous thromboembolism prophylaxis: a qualitative study - Journal of Thrombosis and Haemostasis. Read the full article here. 📖 

🔗 Register now to secure your spot!  Can't make it? Registrants will have early access to the seminar recording.

Past Seminars

Adaptive Trial Design: Advantages and Drawbacks of Bayesian Approaches in Clinical Trials

Date / Time: Thursday, March 30, 2023

Objectives:

1. To present the principles of Bayesian statistics applied to clinical trials;
2. To illustrate the advantages of bayesian approach in order to increase the feasibility of adaptive designs;
3. To report the discussion about possible drawbacks of Bayesian approach in comparison with frequentist approach;
4. To discuss the potential impact of the bayesian approach on the future of evidence based medicine.

Presenter: Eric Vicaut, MD, PhD | AP-HP, Hôpital Lariboisière - Fernand-Widal, Université Paris Cité, Paris, France

The Future of Interventional Cohort Studies & Insights from the RIVA-SVT Study

Date / Time: May 19, 2022

Learning Objective: Showcasing the international "Treatment of Splanchnic Vein Thrombosis With Rivaroxaban" (RIVA-SVT) Study followed by focused presentation on the Future of Intentional Cohort Studies.

Presenters: Walter Ageno, M.D. University of Insubria, Italy; Nicoletta Riva, M.D. Ph.D. University of Malta, Malta

A Proposed Definition of Postpartum Hemorrhage (PPH) & Insights from the HIGHLOW Study

Date / Time: February 9, 2022

Objective: Showcasing the international HIGHLOW Study followed by a proposed definition of PPH

Presenters:

• Laurent Bertoletti, M.D. Ph.D. (INNoVTE - France)
• Bernard Tardy, M.D. Ph.D. (INNoVTE - France)
• Saskia Middeldorp, M.D. Ph.D. (Dutch Thrombosis Network - the Netherlands

Building Patient Engagement in Thrombosis Research 

Date / Time: November 3, 2021

Objective: Showcasing two unique national efforts to improve and integrate patient engagement in clinical VTE / thrombosis research

Featuring: 

• Dr. Fionnuala Ni Ainle |  Ann Marie O’Neill ( INViTE / Thrombosis Ireland -  Ireland)
• Dr. Lisa Duffett | Carol West (CanVECTOR - Canada)