International Network of VENous Thromboembolism Clinical Research Networks

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The Center for Thrombosis and Hemostasis (CTH) is one of eight model centers funded by the German Federal Ministry of Education and Research (BMBF) as part of the national program "Integrated Research and Treatment Centers (IFB)". The objectives of this program are to create an attractive environment for cutting-edge clinical research, better career options for young scientists and a high quality of patient-centered research.

The aim of CTH is to improve the research and treatment of thrombosis and hemostatic disease. Through exemplary, interdisciplinary and integrative structures, a national reference center was set up in the first FP. The translational link between basic scientists and clinicians stimulates innovative principles of diagnosis and treatment. A structured junior research program has created attractive career paths at the interface of science and clinic, which are also available in the second FP. The CTH promotes sustained specialization in thrombosis / hemostasis in Mainz and, moreover, an area that is both clinically and experimentally highly interdisciplinary.

Council Members

Stavros Konstantinides

Stavros Konstantinides, MD, PhD

Dr. Konstantinides is appointed Full Professor for Clinical Trials and Medical Director of the multidisciplinary Center for Thrombosis and Haemostasis (CTH) at the University of Mainz, Germany. The CTH is dedicated to integrated patient care and translational research, and funded by the federal German government. Dr. Konstantinides is also appointed Professor of Cardiology at the Democritus University of Thrace, Greece. He graduated from the Medical School of the Aristotle University in Thessalonica, Greece, in 1987 with honors. He then completed his clinical training in Cardiology and defended his thesis at the University of Freiburg Germany. In 1993, he published his thesis as first author in the New England Journal of Medicine. He has worked as consultant cardiologist, Assistant and Assocciate Professor of Medicine at the Universities of Freiburg and Goettingen, Germany, and as a research associate and visiting professor at the Department of Vascular Biology, the Scripps Research Intitute, La Jolla, CA, USA.

For the past 25 years, his research has been focusing on basic mechanisms of thrombosis, and on the risk stratification and risk-adapted antithrombotic management of venous thromboembolism. He has published over 210 papers in peer-reviewed journals with a cumulative impact factor of almost 1,000 and over 9,000 personal citations, and more than 25 book chapters. He has designed and coordinated, and/or has been principal investigator of several high-impact national and international multicenter trials, 7 of which have been published in the New England Journal of Medicine. His research has funded by national and European peer reviewed granting agencies for over 15 years.

Dr. Konstantinides is leading member of numerous national and European committees, working groups and networks focusing on the pulmonary circulation and right ventricular function as well as on continuing medical education and early-stage career support. Between 2012 and 2014, he chaired the European Society of Cardiology (ESC) task force for the 2014 update of the Guidelines on the Management of Acute Pulmonary Embolism. Currently (2014-2016), he chairs the ESC’s Working Group on Pulmonary Circulation and Right Ventricular Function.


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